21C Museum Hotel St Louis Saint Louis Exterior photo21C Museum Hotel St Louis Saint Louis Exterior photo21C Museum Hotel St Louis Saint Louis Exterior photo
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From199US$ /night
Check-in
02Jun2026Select date
Check-out
03Jun2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Close to the Gateway Arch
Great
8.4
8.8
/10
4.2
4.1
/5

Positioned about 15 minutes' walk from the Citygarden Sculpture Park, the 4-star boutique-style 21C Museum Hotel St Louis Saint Louis presents an event space ideal for different occasions. Spanish cuisine plus an indoor swimming pool are provided in the contemporary hotel, located in proximity to the City Museum.

Location

The hotel lies in the very heart of Saint Louis, 300 metres from the Gothic Revival Centenary Methodist Episcopal Church. The Milles Fountain is within reach of the 21C Museum Hotel St Louis Saint Louis, while Lambert airport is 25 km from it.

The property is also a mere 1.2 km from the 501 non-profit National Blues Museum and Civic Center Transit Center bus station is nearly a 10-minute walk away.

This Saint Louis hotel is situated near Union train station, merely 1 km away.

Rooms

The 137 rooms at 21C Museum Hotel St Louis are equipped with comforts such as an iron and an air conditioner, as well as a flat-screen TV with satellite channels and pay-per-view channels.

Eat & Drink

Idol Wolf, an onsite restaurant, is open for dinner. The lounge bar provides you with a place to unwind.

Leisure & Business

The 21C Museum Hotel St Louis offers options for sports and relaxation in a steam room and a Jacuzzi, or at a fitness centre. For guests who like to stay in shape, this accommodation offers sports facilities such as a personal trainer and yoga instruction. The onsite spa amenities include a spa salon. The 21C Museum Hotel St Louis also provides meeting rooms for those arriving on business.

“In my view, this property distinguishes itself through its commitment to integrating art and culture into the guest experience. The indoor pool and wellness amenities offer a luxurious touch, while its location in Downtown St Louis makes it a convenient base for exploring the city's attractions, in my opinion. A great choice for travelers looking to immerse themselves in both comfort and creativity.”
Hotel logo
James DavidEditor-in-Chief at Dogfriendly-hotels
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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
47 m² 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
40 m² 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
29 m² 
1 King-size bed
Shower
Heating
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Rates & availability calendar

See current prices and availability for your chosen dates!

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable
Facilities: Great
8.7/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
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Hotel location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
Explore Saint Louis
Local Highlights
Top Attractions
Activities
Dining
Entertainment
City Museum
City Museum
5 minutes walking
An eclectic indoor/outdoor playground for all ages, featuring slides, tunnels, and art installations, perfect for family fun.
Campbell House Museum
Campbell House Museum
2 minutes walking
A historic house museum showcasing Victorian-era art and antiques, providing guided tours that reveal St. Louis's history.
Stifel Theatre
Stifel Theatre
8 minutes walking
A beautifully restored venue hosting concerts and performances, known for its stunning architecture and acoustics.
The Gateway Arch
The Gateway Arch
25 minutes walking
An iconic symbol of St. Louis, offering an incredible view of the city from its observation deck and engaging visitor center.
Visit the Citygarden Sculpture Park
15 minutes walking
An outdoor park with sculptures, gardens, and water features; ideal for leisurely strolls and relaxation.
Kayaking at the Mississippi River
5 minutes driving
Thrill-seekers can rent kayaks and explore the mighty Mississippi River, a fantastic way to enjoy the urban landscape.
The Last Kitchen
The Last Kitchen
5 minutes walking
A casual spot offering a menu of American comfort food with local ingredients, perfect for families. Reservations recommended.
Rooftop Cafe at City Museum
Rooftop Cafe at City Museum
5 minutes walking
A rooftop dining experience with stunning views and a menu featuring local fare-unique atmosphere with a fun vibe.
National Blues Museum
National Blues Museum
16 minutes walking
Celebrating St. Louis's rich blues heritage, this interactive museum hosts events and exhibits perfect for music lovers.
Flannery's
Flannery's
5 minutes walking
A lively pub featuring local craft beers and live music, providing a great spot for relaxation after a day of exploring.
Local transport and travel tips
City Centre
Saint Louis8 min  ·  600 m
Airports
Lambert (STL)33 min  ·  21.8 km
MidAmerica St. Louis/Scott Air Force Base (BLV)62 min  ·  40.8 km
Train
Union Station9 min  ·  700 m
Bus
Bus stop3 min  ·  200 m
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137

Reviews and Ratings

Feedback about 21C Museum Hotel St Louis from previous guests about their experience.
Review score
Based on 1642 verified reviews
8.3/10
Great
78%
Recommend
Breakfast
6.6/10
Cleanliness
8.8/10
Comfort
8.7/10
Facilities
8.7/10
Free Wi-Fi
7.7/10
Location
8.6/10
Paid Wi-Fi
5.9/10
Staff
8.6/10
Value for money
8.0/10
Pros
Amazing staff
Clean rooms
Well curated museum
Cons
Expensive parking
Missing supplies
Guest reviews
based on 1035 reviews
8.4/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About 21C Museum Hotel St Louis
What attractions are nearby 21C Museum Hotel St Louis?
Nearby attractions include the Gateway Arch (3 km), Old Courthouse (2 km), and City Museum (500 m).
What time can guests check in and out of 21C Museum Hotel St Louis?
Check-in is at 16:00, and check-out is by 11:00.
Is there parking available at 21C Museum Hotel St Louis?
Valet parking is available on-site for guests.
What amenities can guests expect in the rooms at 21C Museum Hotel St Louis?
Rooms are equipped with air conditioning, a flat-screen TV, a safe deposit box, and a private bathroom with free toiletries.
What dining options are available at 21C Museum Hotel St Louis?
The hotel features an on-site restaurant that offers innovative cuisine and a bar/lounge area.
What wellness facilities does 21C Museum Hotel St Louis offer?
Guests can enjoy an indoor swimming pool, a hot tub, a spa & wellness centre, and fitness facilities.
Are pets allowed at 21C Museum Hotel St Louis?
Pets are allowed with potentially applicable charges.
What is the distance from 21C Museum Hotel St Louis to St. Louis Lambert International Airport?
The hotel is located 21 km from St. Louis Lambert International Airport.
What type of services does 21C Museum Hotel St Louis provide for business travelers?
The hotel offers a business centre and meeting facilities equipped with advanced audiovisual technology.
Can guests enjoy breakfast at 21C Museum Hotel St Louis?
An American breakfast is available for guests at the hotel.
What are some nearby dining options from 21C Museum Hotel St Louis?
Nearby dining options include The Sliced Pint Tap & Pizza, Rooftop Cafe at City Museum, and Red Oak Biscuits, all within 0.5 km.

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Check-in
02Jun2026Select date
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03Jun2026Select date
Rooms and Guests2 Guests, 1 Room